The largest analysis of Canarian genetics
The Research Unit of the University Hospital Nuestra Señora de Candelaria in Tenerife, has presented greater Canarian DNA analysis. The objective of this study is to determine the relationships of Canarian genetic diversity with the most frequent complex pathologies in the Archipelago.
It is an investigation developed in collaboration with the Institute of Renewable Energies of Tenerife (ITER). The study is essential because in the future, it will be key to develop new studies in search of genetic risk factors in the Islands.
DNA characteristics of the Canarian population
The analysis was carried out during three years of work of the team led by the group of researchers of the Research Unit of the University Hospital Nuestra Señora de Candelaria. In it, through DNA 'chips' and massive sequencing techniques, they have brought to light data of the complete genome of more than 400 adult women and men of the islands, whose four grandparents had been born on the same island. Information that was collated together with the existing data on the Canarian aboriginal population.
Diabetes, asthma and allergy in the Canarian population
The research confirms that the Canarian DNA presents a distinctive genetics. This is a consequence of different factors such as:
|The geographical isolation of the Islands||Adaptation to the environment of its inhabitants||The historical mix of the prehispanic population of the Archipelago with European individuals and the sub-Saharan area|
It is estimated that the last great 'miscegenation' of these characteristics took place approximately 450 years ago and is evident throughout the island territory. This genetic inheritance can explain the prevalence of genetic variants related to complex diseases such as diabetes, asthma and allergy. This type of pathologies are very frequent in the current Canarian population.
This work opens a door to research in the field of health and biomedicine. Through the identification of genetic variants of risk of various pathologies, more information about the origin of them and advance in their clinical application and in the development of precision personalized medicine can be obtained.
In short, this work opens the door to continue investigating the identification of genetic variants of risk of different pathologies. But the most important thing is that thanks to the data obtained, you can create references for the development of personalized medicine on the islands. Create a proper genetic catalog to know and create references and, thus, be able to adapt medicine to the population context.